Bedaquiline

Overview
Catalog #	bs-82856c-5-mg
Product Name	Bedaquiline
Specifications
Storage Buffer	Off-white to white solid
Storage Condition	RT
Target
Product Information	Bedaquiline is a clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains.1 It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE)2 and subunit 3 of ATP synthase inhibiting ATP production.4 Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.5
Description	CAS Number: 843663-66-1 Chemical Name: (1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol Molecular weight: 555.50 Formula: C32H31BrN2O2 Solubility: DMSO (10 mg/ml) Physical Properties: White solid Purity: 99% by HPLC, NMR (Conforms)