BI-9564

Overview
Catalog #	bs-82846c-5-mg
Product Name	BI-9564
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Potent, selective, and cell permeable inhibitor of the BRD9 bromodomain, a subunit of the switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex (IC50 = 75 nM).1 It displayed antitumor activity in an acute myeloid leukemia xenograft model. BI-9564 displayed cytotoxic and anti-proliferative effects in 5 rhabdoid tumor cell lines.2
Description	CAS Number: 1883429-22-8 Chemical Name: 4-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridine-1-one Molecular weight: 353.42 Formula: C20H23N3O3 Solubility: DMSO (5 mg/ml) Physical Properties: White solid Purity: >98% by HPLC, NMR (Conforms)