BD1047 dihydrobromide

Overview
Catalog #	bs-82825c-5-mg
Product Name	BD1047 dihydrobromide
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	BD1047 is a potent and selective sigma-1 antagonist (IC50’s: sigma1 = 0.93nM, sigma2 = 47nM). .1 Pretreatment of mice with BD1047 reduced convulsions, lethality, and locomotor activity induced by cocaine.2 BD1047 attenuated high fat diet-induced peripheral neuropathy in mice.3 BD1047 displayed antinociceptive effects in several rodent pain models.4-6 It also inhibits the beta-adrenoreceptor (IC50 = 145 nM).1
Description	CAS Number: 138356-21-5 Chemical Name: N-[2-(3,4 Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide Molecular weight: 437.04 Formula: C13H20Cl2N2·2HBr Solubility: DMSO (20 mg/ml) Water (20 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (Conforms)