NE-100
Overview | |
Catalog # | bs-82820c-5-mg |
Product Name | NE-100 |
Specifications | |
Storage Buffer | Pale pink/purple solid |
Storage Condition | -20°C |
Target | |
Product Information | NE-100 is potent inhibitor of the sigma receptor () with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM).1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3 |
Description | CAS Number: 149409-57-4 Chemical Name: 4-Methoxy-3-(2-phenylethoxy)-N,N,dipropylbenzeneethanamine hydrochloride Molecular weight: 391.97 Formula: C23H33NO2·HCl Solubility: DMSO (>25 mg/ml) Water (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms) |