TIC10

Overview
Catalog #	bs-82788c-5-mg
Product Name	TIC10
Specifications
Storage Buffer	Off-white to beige solid
Storage Condition	-20°C
Target
Product Information	TIC10 (1616632-77-9) is novel anti-cancer compound that acts via early-stage integrated stress response activation leading to selective cancer cell death.1-3 TIC10 potently activates mitochondrial caseinolytic protease P (ClpP) causing eIF2-independent induction of ATF4 and Akt/ERK/Foxo3a/DR5/TRAIL-dependent apoptosis.4 Currently in clinical trials.
Description	CAS Number: 1616632-77-9 Chemical Name: 7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one Molecular weight: 386.49 Formula: C24H26N4O Solubility: DMSO (25 mg/ml) Physical Properties: Pale yellow solid Purity: 98% by TLC