Ranolazine

Overview
Catalog #	bs-82704c-10-mg
Product Name	Ranolazine
Specifications
Storage Buffer	Colorless film
Storage Condition	RT
Target
Product Information	Ranolazine is an FDA-approved drug used for the treatment of chronic angina. It inhibits the late inward sodium current in heart muscle leading to decreased intracellular calcium levels.1 It blocks Nav 1.4, 1.5, 1.7 and 1.8 (IC50’s = 2.42, 6.22, 1.72(10.33), 21.53 µM respectively.
Description	CAS Number: 142387-99-3 Chemical Name: (±)-N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)-propyl]piperazin-1-yl]acetamide Molecular weight: 427.54 Formula: C24H33N3O4 Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC (10% methanol/methylene chloride; Rf = 0.63)