Erastin

Overview
Catalog #	bs-82674c-5-mg
Product Name	Erastin
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).4
Description	CAS Number: 571203-78-6 Chemical Name: 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone Molecular weight: 547.04 Formula: C30H31ClN4O4 Solubility: DMSO (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)