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Dihydroergotamine mesylate

Overview
Catalog # bs-82673c-10-mg
Product Name Dihydroergotamine mesylate
Specifications
Storage Buffer Cream colored solid
Storage Condition -20°C
Target
Product Information Dihydroergotamine mesylate (6190-39-2) is a full agonist at serotonin 5HT1B and 5HT1D receptors, IC50= 2 and 2.2 nM respectively1 and also at 5HT1A and 5HT1F receptors2. One of the oldest agents for treatment of migraine.3 Also acts as a potent vasoconstrictor and alpha-adrenergic antagonist.4
Description CAS Number: 6190-39-2

Chemical Name: (5’a,10a)-9,10-Dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)ergotaman-3′,6′,18-trione, mesylate

Molecular weight: 679.79

Formula: C33H37N5O5 • CH3SO3H

Solubility: DMSO (25 mg/ml)

Physical Properties: Off-white solid

Purity: >98% by HPLC, NMR (Conforms)