TRO19622

Overview
Catalog #	bs-82655c-5-mg
Product Name	TRO19622
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP).1 Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage.2 Inhibits MPTP opening and protects neurons from apoptosis.3 Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model.4
Description	CAS Number: 22033-87-0 Chemical Name: Cholest-4-en-3-one oxime Molecular weight: 399.65 Formula: C27H45NO Solubility: DMSO (20 mg/ml) Ethanol (25 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)