DPN
| Overview | |
| Catalog # | bs-82609c-5-mg |
| Product Name | DPN |
| Specifications | |
| Storage Buffer | Lyophilized solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent estrogen ERβ receptor agonist. Displays a 70-fold selectivity over ERα, EC50 = 0.85 and 66 nM, respectively.1 Regulates expression of GluR1, 2 and 3 in rat hippocampus.2 Ameliorates portal hypertension in a carbon tetrachloride-induced liver cirrhosis rat model.3 Stimulates proliferation of androgen-independent prostate cancer cell line PC-3 via a novel pathway involving ERβ-mediated activation of β-catenin.4 A useful tool for elucidating the biological function of ERβ.5 |
| Description | CAS Number: 1428-67-7 Chemical Name: 2,3-bis(4-Hydroxyphenyl)-propionitrile Molecular weight: 239.27 Formula: C15H13NO2 Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms) |
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