Saracatinib

Overview
Catalog #	bs-82607c-5-mg
Product Name	Saracatinib
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Potent and selective inhibitor of Src family kinases, IC50=4-10 nM for Src, c-Yes, Fyn, Lyn, Blk, Fgr and Lck.1 Demonstrates potent antimigratory, anti-invasive and antiproliferative activity and inhibits metastasis in a mouse model of bladder cancer.2 Inhibits MERS- CoV at early stages of the viral life cycle at mM concentrations.3,4 Rescues memory performance and reduces phospho-Tau accumulation in traumatic tauopathy.5 Rescues memory deficits and synaptic depletion in an Alzheimer’s mouse model.6
Description	CAS Number: 379231-04-6 Chemical Name: N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine Molecular weight: 542.03 Formula: C27H32ClN5O5 Solubility: DMSO (50 mg/ml) and ethanol (54 mg/mL with warming) Physical Properties: White solid Purity: >98% HPLC, NMR (Conforms)