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5-Ethynyl-2'-deoxyuridine

Overview
Catalog # bs-82583c-50-mg
Product Name 5-Ethynyl-2'-deoxyuridine
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information A novel agent for fast and sensitive detection of DNA synthesis in vivo1. 5-EdU is incorporated into proliferating cells followed by detection with a fluorescent azide using click ligation1. In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. May be used for studying cell proliferation in the central nervous system and may be combined with BrdU staining in a novel protocol allowing for double labeling of DNA synthesis2.
Description CAS Number: 61135-33-9

Chemical Name: 2’-Deoxy-5-ethynyluridine

Molecular weight: 252.23

Formula: C11H12N2O5

Solubility: DMSO (10 mg/ml)

Physical Properties: white or off-white solid

Purity: 98% by HPLC NMR (Conforms)