Baicalein
Overview | |
Catalog # | bs-82579c-100-mg |
Product Name | Baicalein |
Specifications | |
Storage Buffer | Yellow solid |
Storage Condition | -20°C |
Target | |
Product Information | Inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis1. Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC50=0.64 µM for 12-LO and 1.6 µM for 15-LO)2. Displays antiinflammatory activity and inhibits adjuvant-induced arthritis. Also inhibits prolyl oligopeptidase (IC50=36 µM)3. |
Description | CAS Number: 491-67-8 Chemical Name: 5,6,7-Trihydroxyflavone Molecular weight: 270.24 Formula: C15H10O5 Solubility: DMSO (15 mg/ml) Physical Properties: Yellow or yellow-green solid Purity: 98% by TLC, NMR (Conforms) |