Griseofulvin

Overview
Catalog #	bs-82571c-100-mg
Product Name	Griseofulvin
Specifications
Storage Buffer	Cream colored solid
Storage Condition	RT
Target
Product Information	Antifungal antimitotic agent. Induces apoptosis of human germ cell tumor cells via disruption of connexin 43/tubulin association concomitant with enhanced translocation of connexin 43 from the cytoplasm to the nucleus1. Inhibits the growth of adrenocortical cancer cells in vitro2. Inhibits centrosome clustering, induces spindle multipolarity, mitotic arrest and cell death in multiple tumor cell lines but not in diploid fibroblasts and keratinocytes with normal centrosome content3.
Description	CAS Number: 126-07-8 Chemical Name: Fermentation product from Penicillium sp. Molecular weight: 352.77 Formula: C17H17ClO6 Solubility: DMSO (40 mg/ml) Ethanol (5 mg/ml) DMF (50 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMr (Conforms)