8-pCPT-2-O-Me-cAMP-AM
| Overview | |
| Catalog # | bs-82569c-100-ug |
| Product Name | 8-pCPT-2-O-Me-cAMP-AM |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability. |
| Description | CAS Number: 1152197-23-3 Chemical Name: 8-(4-Chlorophenylthio)-2’-O-methyladenosine-3’,5’-cyclic monophosphate, acetoxymethyl ester Molecular weight: 557.91 Formula: C20H21ClN5O8PS Solubility: DMSO (50 mg/ml) Physical Properties: solid Purity: 97% by HPLC |
Powered by Bioz