Obatoclax
Overview | |
Catalog # | bs-82547c-5-mg |
Product Name | Obatoclax |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | A novel Bcl-2 homology domain-3 (BH3) mimetic1. Inhibits primary acute myeloid leukemia (AML) progenitor cell proliferation (IC50=0.18 μM) and induces apoptosis in primary AML cells (IC50= 3.6 μM)2. Synergizes with other agents such as chloroquine3 and cytarabine4 in cytotoxicity against a variety of cancer cells. |
Description | CAS Number: 803712-79-0 Chemical Name: 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate Molecular weight: 413.50 Formula: C20H19N3O · CH3SO3H Solubility: DMSO (5 mg/ml) Physical Properties: Purple solid Purity: 98% by TLC |