Montelukast sodium

Overview
Catalog #	bs-82532c-50-mg
Product Name	Montelukast sodium
Specifications
Storage Buffer	Olive green solid
Storage Condition	-20°C
Target
Product Information	Potent, selective CysLT1 receptor (leukotriene D4) antagonist (Ki = 0.18 nM).1,2 Displays anti-inflammatory and anti-asthmatic effects. Clinically useful agent for treatment of chronic asthma.3 Attenuates chronic brain injury after focal cerebral ischemia in rodent models.4 Decreases blood brain barrier dysfunction in mouse models.5 Blockade of GPR17 by montelukast elevates neural stem and progenitor proliferation.6
Description	CAS Number: 151767-02-1 Chemical Name: 2-[1-[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate, sodium salt Molecular weight: 608.17 Formula: C35H35ClNO3S Na Solubility: DMSO (60 mg/ml) Water (30 mg/ml) Ethanol (60 mg/ml) Physical Properties: Solid Purity: 98% by HPLC, NMR (Conforms)