SirtAct

Overview
Catalog #	bs-82531c-5-mg
Product Name	SirtAct
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Sirt1 activator (233% at 10 μM)1 Suppresses TNFα release from THP-1 cells and stimulates adipogenesis in 3T3L1 cells1. SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice2. Inhibits NFκB activation and reduces inflammatory cytokine production in lamina propria mononuclear cells from IBD patients3. Prevents and cures experimental colitis in a mouse model3.
Description	CAS Number: 839699-72-8 Chemical Name: 2-Amino-N-cyclopentyl-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide Molecular weight: 367.46 Formula: C20H25N5O2 Solubility: DMSO (50 mg/ml) Ethanol (20 mg/ml) Physical Properties: Olive green solid Purity: 98% by TLC, NMR (Conforms)