Norquetiapine · 2HCl

Overview
Catalog #	bs-82529c-50-mg
Product Name	Norquetiapine · 2HCl
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Pharmacologically active metabolite of quetiapine.1 Exhibits distinct pharmacological activity from quetiapine and plays an important role in its antidepressant activity.2 Activates ERK1/2 and induces release of BDNF in C6 glioma cells which may contribute to the antidepressant properties of quetiapine.3 Inhibits the norepinephrine transporter which may contribute to the antipsychotic activity of quetiapine.4
Description	CAS Number: 111974-74-4 Chemical Name: 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride Molecular weight: 368.32 Formula: C17H17N3S 2HCl Solubility: DMSO, Methanol Water Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms)