Cilostamide

Overview
Catalog #	bs-82527c-5-mg
Product Name	Cilostamide
Specifications
Storage Buffer	Yellow/Orange Oil
Storage Condition	RT
Target
Product Information	Selective inhibitor of phosphodiesterase-3 (PDE3). Displays limited selectivity for PDE3A versus PDE3B (IC50 = 27 and 50 nM)1,2. Blocks PKB/Akt signaling pathway downstream via inhibition of Akt-activated PDE3B3. Reverses the effect of leptin on food intake and body weight4.
Description	CAS Number: 68550-75-4 Chemical Name: N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide Molecular weight: 342.44 Formula: C20H26N2O3 Solubility: DMSO (30 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)