THI

Overview
Catalog #	bs-82505c-5-mg
Product Name	THI
Specifications
Storage Buffer	Solution in water with 5% acetonitrile at 50 µg/0.5 mL
Storage Condition	-20°C
Target
Product Information	THI was identified as a biologically active impurity in caramel food coloring.1 It is a potent inhibitor of sphingosine-1-phosphate (S1P) lyase.2 It disrupts lymphocyte egress from lymphoid tissue by interfering with S1P gradients.3,4 The novel immunomodulatory activity of THI and its biochemical mechanism may represent a new target for the development of new generation of immunosuppressants.5
Description	CAS Number: 94944-70-4 Chemical Name: 2-Acetyl-4-tetrahydroxybutyl Imidazole Molecular weight: 230.22 Formula: C9H14N2O5 Solubility: Water (10 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)