SB-431542

Overview
Catalog #	bs-82496c-5-mg
Product Name	SB-431542
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM)1,2. Inhibits TGFβ-induced proliferation of human osteosarcoma cells3. Ehances growth and integrity of embryonic stem cell-derived endothelial cells4. A frequently used agent employed in numerous stem cell differentiation protocols5. Cell permeable.
Description	CAS Number: 301836-41-9 Chemical Name: 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide Molecular weight: 384.40 Formula: C22H16N4O3 Solubility: DMSO (30 mg/ml) Ethanol (3 mg/ml) Physical Properties: Yellow solid Purity: 99% by HPLC NMR (Conforms)