Rofecoxib

Overview
Catalog #	bs-82493c-50-mg
Product Name	Rofecoxib
Specifications
Storage Buffer	Pale yellow or off-white solid
Storage Condition	RT
Target
Product Information	Potent and selective COX-2 inhibitor with 1000-fold selectivity over COX-1, IC50=26 nm vs >50 μM1. Potent nonsteroidal anti-inflammatory agent1. Clinically useful NSAID which was withdrawn from use due to cardiovascular side effects3.
Description	CAS Number: 162011-90-7 Chemical Name: 4-[4-(methylulfonyl)phenyl]-3-phenyl-2(5H)-furanone Molecular weight: 314.36 Formula: C17H14O4S Solubility: DMSO (50 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC, NMR (conforms)