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Memantine HCl

Overview
Catalog # bs-82470c-50-mg
Product Name Memantine HCl
Specifications
Storage Buffer Yellow solid
Storage Condition RT
Target
Product Information An NMDA noncompetitive, low affinity, open channel blocker, IC50~1 μM at -60 mV in rat retinal ganglion cells.1 Displays neuroprotective effects in excitotoxic conditions.2 Preferentially blocks excessive NMDA receptor activity without disrupting normal activity.3 A clinically well tolerated drug with therapeutic potential in numerous CNS degenerative disorders.4 In clinical use for Alzheimer’s disease.5
Description CAS Number: 41100-52-1

Chemical Name: 3,5-Dimethyl-tricyclo[3.3.1.13,7]decam-1-amine HCl

Molecular weight: 215.76

Formula: C12H21N HCl

Solubility: Water (20 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC, NMR (conforms)