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TPCK

Overview
Catalog # bs-82454c-100-mg
Product Name TPCK
Specifications
Storage Buffer Beige solid
Storage Condition -20°C
Target
Product Information TPCK is an irreversible inhibitor of the serine protease chymotrypsin.1 It also inhibits certain cysteine proteases (bromelain, ficin, papain).1 TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle.2
Description CAS Number: 402-71-1

Chemical Name: N-p-Tosyl-L-phenylalanine chloromethyl ketone

Molecular weight: 351.80

Formula: C17H18ClNO3S

Solubility: DMSO (10 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC, NMR Conforms