Tryptanthrin

Overview
Catalog #	bs-82439c-5-mg
Product Name	Tryptanthrin
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	A indoloquinazoline alkaloid found in various plant species and possessing intriguing pharmacological activities.1 Suppresses activation of BV2 microglia cells following LPS treatment and reduces production of proinflammatory cytokines via Nrf2, HO-1 and NFκB signaling.2 Displays antiinflammatory activity targeting IL-17.3 Inhibits indoleamine 2,3-dioxygenase 2 (IDO2) with an IC50 of 5-17 μM.4 Induces growth inhibition and neuronal differentiation in human neuroblastoma LA-N-1 cells.5
Description	CAS Number: 13220-57-0 Chemical Name: Indolo(2,1-b)quinazoline-6,12-dione Molecular weight: 248.24 Formula: C15H8N2O2 Solubility: DMSO (30 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC, NMR (Conforms)