H89 · 2HCl

Overview
Catalog #	bs-82411c-5-mg
Product Name	H89 · 2HCl
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	H-89 is a commonly used inhibitor of protein kinase A (PKA IC50 = 140 nM). Inhibits a variety of other kinases including S6K1 (IC50 = 80 nM), MSK1 (120 nM), ROCK II (270 nM), PKBα (2.6 µM), PKD, PRK2, RSK1 and 2, SGK, AMPK, CHK1 and MAPKAP-K1b (2.8 µM).1,2
Description	CAS Number: 127243-85-0 Chemical Name: N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride Molecular weight: 519.28 Formula: C20H20BrN3O2S·2HCl Solubility: DMSO (50 mg/ml) Water (10 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms)