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Leptomycin B

Overview
Catalog # bs-82382c-1-mg
Product Name Leptomycin B
Specifications
Storage Buffer white or off white solid
Storage Condition -20°C
Target
Product Information Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3.
Description CAS Number: 87081-35-4

Chemical Name:

Molecular weight: 540.75

Formula: C33H48O6

Solubility: Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO

Physical Properties: Solution in ethanol (1mg/ml)

Purity: 99% by HPLC, NMR (Conforms)