Ezetimibe

Overview
Catalog #	bs-82360c-20-mg
Product Name	Ezetimibe
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter.1 Undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1.2 Inhibits dengue virus infection in Huh-7 cells by blocking cholesterol transport.3 Ameliorates steatohepatitis by activation of autophagy and inhibition of NLRP3 inflammasome.4
Description	CAS Number: 163222-33-1 Chemical Name: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidine-2-one Molecular weight: 409.43 Formula: C24H21F2NO3 Solubility: DMSO (25 mg/ml) Ethanol (15 mg/ml) Physical Properties: White or off-white solid Purity: 98% by TLC NMR (Conforms)