Exo2

Overview
Catalog #	bs-82336c-5-mg
Product Name	Exo2
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Exo2 disrupts the Golgi apparatus and stimulates Golgi-ER fusion in mammalian cells.1 May be used to completely ablate the Golgi apparatus.1 Like brefeldin A (BFA), it inhibits anterograde transport and disrupts morphology of the trans-Golgi network (TGN) but unlike BFA, it does not induce tubulation and merging of the TGN and endosomal compartments.2 It perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network, in contrast to cholera toxin.1,2 Accelerates degradation of perilipin-2 proteins.3
Description	CAS Number: 304684-77-3 Chemical Name: 2-Methoxy-4-[(5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Molecular weight: 354.43 Formula: C18H18N4O2S Solubility: DMSO (25 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC, NMR (Conforms)