TGN-020

Overview
Catalog #	bs-82316c-10-mg
Product Name	TGN-020
Specifications
Storage Buffer	Orange solid
Storage Condition	RT
Target
Product Information	Aquaporin 4 channel blocker, IC50 = 3.1 μM.1 Reduces ischemic cerebral edema in a mouse model of focal cerebral ischemia using MRI.2 Increases regional cerebral blood flow as determined in wild-type and AQP-4 knockout mice.3 Reduces brain edema when administered after onset of ischemia in rat models.4
Description	CAS Number: 51987-99-6 Chemical Name: N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide Molecular weight: 206.22 Formula: C8H6N4OS Solubility: DMSO (10 mg/ml with warming) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms)