DC260126

Overview
Catalog #	bs-82308c-5-mg
Product Name	DC260126
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	A GPR40 receptor antagonist1. Suppresses fatty acid-induced elevation of intracellular Ca++. Inhibits palmitic acid potentiated glucose–stimulated insulin secretion in Min6 pancreatic β cells in vitro. Lowers serum insulin levels, increases insulin sensitivity2 in obese Zucker rats (6 mg/kg)2. Reduces pancreatic β cell apoptosis in obese diabetic (db/db) rats3. Protects Min6 β cells from palmitic acid-induced ER stress and apoptosis4
Description	CAS Number: 346692-04-4 Chemical Name: N-(4-Butylphenyl)-4-fluorobenzenesulfonamide Molecular weight: 307.37 Formula: C16H18NO2S Solubility: DMSO (80 mg/ml) Ethanol (80 mg/ml) Physical Properties: Brown waxy solid Purity: 98% by HPLC NMR (Conforms)