Fascaplysin
Overview | |
Catalog # | bs-82298c-1-mg |
Product Name | Fascaplysin |
Specifications | |
Storage Buffer | Off-white solid |
Storage Condition | -20°C |
Target | |
Product Information | A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 μM) and is less selective for Cdk6/D1 (IC50 = 3.4 μM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3. |
Description | CAS Number: 114719-57-2 Chemical Name: 12,13-Dihydro-13-oxopyrido[1,2-a:3,4-b’]diindol-5-ium chloride Molecular weight: 306.75 Formula: C18H11ClN2O4 Solubility: DMSO (20 mg/ml) water (2 mg/ml) Physical Properties: Dark red-brown solid Purity: 98% by TLC, NMR (Conforms) |