RVX-208

Overview
Catalog #	bs-82278c-5-mg
Product Name	RVX-208
Specifications
Storage Buffer	Light brown solid
Storage Condition	-20°C
Target
Product Information	RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD11,2. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo3. Reduces atherosclerosis4.
Description	CAS Number: 1044870-39-4 Chemical Name: 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinzolinone Molecular weight: 370.41 Formula: C20H22N2O5 Solubility: DMSO (75 mg/ml) Ethanol (4 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)