AG-1517 · HCl
| Overview | |
| Catalog # | bs-82211c-5-mg |
| Product Name | AG-1517 · HCl |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | RT |
| Target | |
| Product Information | An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3. |
| Description | CAS Number: 153436-54-5 Chemical Name: 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride Molecular weight: 360.21 Formula: C16H14BrN3O2 Solubility: DMSO (5 mg/ml) Physical Properties: white or off-white solid Purity: 98% by TLC, NMR (Conforms) |
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