WP-1130

Overview
Catalog #	bs-82192c-5-mg
Product Name	WP-1130
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	A novel DUB inhibitor directly inhibiting USP9x, USP5, USP14 and UCH37 inducing rapid accumulation of polyubiquitinated proteins. Triggers tumor cell apoptosis.1 Blocks Jak2 signaling via Jak2 ubiquitination.2 Causes ablation of the oncogenic transcription factor ERG in prostate cancer cells.3
Description	CAS Number: 856243-80-6 Chemical Name: (S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide Molecular weight: 384.28 Formula: C19H18BrN3O Solubility: DMSO (45 mg/ml) Ethanol (25 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC, NMR (conforms)