b-AP15 (NSC-687852)
| Overview | |
| Catalog # | bs-82188c-5-mg |
| Product Name | b-AP15 (NSC-687852) |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Abrogates the deubiquitinating activity of the 19S regulatory particle by inhibiting ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) resulting in accumulation of polyubiquitin in cells. b-AP15 induces tumor cell apoptosis and tumor progression in four different solid tumor models in vivo. |
| Description | CAS Number: 1009817-63-3 Chemical Name: 3,5-bis[(4-Nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one Molecular weight: 419.40 Formula: C22H17N3O6 Solubility: DMSO (35 mg/ml) Physical Properties: Pale yellow solid. (MP = 170-174°C) Purity: >98% by HPLC |
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