LDN-57444

Overview
Catalog #	bs-82166c-5-mg
Product Name	LDN-57444
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Inhibits ubiquitin C-terminal hydrolase (UCH-L1) (Ki=0.4 M). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Cell permeable.
Description	CAS Number: 668467-91-2 Chemical Name: 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime) Molecular weight: 397.65 Formula: C17H11Cl3N2O3 Solubility: DMSO (20 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC, NMR conforms