New to Bioss? Enjoy 35% of your first order. Use code "FirstOrder35" - Offer valid for new U.S. Customers on direct orders only

7,8-Dihydroxyflavone

Overview
Catalog # bs-82112c-100-mg
Product Name 7,8-Dihydroxyflavone
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information A selective TrkB agonist (Kd=320 nM) with potent neurotrophic activity.1,2 Significantly improves motor deficits, ameliorates brain atrophy and extends survival in the well-characterized N171-82Q Huntington’s disease mouse model.3 Post-traumatic brain injury-treatment promotes neurogenesis in the hippocampus in a mouse model.4 Improves motor performance and motor neuronal survival in an ALS mouse model.5
Description CAS Number: 38183-03-8

Chemical Name: 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one

Molecular weight: 254.25

Formula: C15H10O4

Solubility: DMSO (25 mg/ml) Ethanol (6 mg/ml)

Physical Properties: Yellow or tan solid

Purity: 98% by TLC, NMR Conforms,