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AT-101

Overview
Catalog # bs-82107c-10-mg
Product Name AT-101
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information A small molecule mimic of the BH3 domain of cellular Bcl-2 inhibitors which interferes with the function of Bcl-2-family antiapoptotic proteins. Induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway. Cell permeable.
Description CAS Number: 90141-22-3

Chemical Name:

Molecular weight: 518.56

Formula: C30H30O8

Solubility: DMSO (50 mg/ml) Ethanol (50 mg/ml)

Physical Properties: Light brown solid

Purity: >98% by TLC [ hexene/ethyl acetate; 70:30 Rf = 0.4] NMR (Conforms)