Retinoic acid

Overview
Catalog #	bs-82089c-50-mg
Product Name	Retinoic acid
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	All−trans−Retinoic acid (ATRA; a metabolite of Vitamin A) is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 ATRA promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4
Description	CAS Number: 302-79-4 Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid Molecular weight: 300.44 Formula: C20H28O2 Solubility: DMSO (8 mg/ml) Ethanol (15 mg/ml) Physical Properties: Yellow solid Purity: 98% NMR Conforms