Sivelestat
| Overview | |
| Catalog # | bs-82069c-5-mg |
| Product Name | Sivelestat |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | RT |
| Target | |
| Product Information | Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other proteases. Inhibits NF-κB activation2 and LTB4-induced neutrophil migration in vitro3. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo4. |
| Description | CAS Number: 127373-66-4 Chemical Name: N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium Molecular weight: 456.45 Formula: C20H21N2O7 Solubility: DMSO (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC |
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