AG-879

Overview
Catalog #	bs-82061c-5-mg
Product Name	AG-879
Specifications
Storage Buffer	Yellow solid (MP = 223-224°C)
Storage Condition	-20°C
Target
Product Information	Inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 µM). No inhibition of EGF, or PDGF receptor phosphorylation at typical working concentrations.
Description	CAS Number: 148741-30-4 Chemical Name: 3,5-Di-t-butyl-4-hydroxybenzylidene cyanothioacetamide Molecular weight: 316.47 Formula: C18H24N2OS Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Yellow solid (MP = 223-224°C) Purity: 99% by TLC [5% methanol in methylene chloride, Rf = 0.76] NMR Conforms