VAS-2870

Overview
Catalog #	bs-82050c-5-mg
Product Name	VAS-2870
Specifications
Storage Buffer	Off-white solid
Storage Condition	RT
Target
Product Information	NAD(P)H oxidase (Nox) inhibitor. Abolishes PDGF-mediated Nox activation and ROS production (100% at 10 M). Inhibits PMA-induced oxidative burst in HL-60 cells (IC50=2 µM). Enhances TGF-ß-induced apoptosis in liver tumor cells.
Description	CAS Number: 722456-31-7 Chemical Name: 3-Benyl-7-(2-benzoxazolyl)yhio-1,2,3-triazolo(4,5-d)pyrimidine Molecular weight: 360.4 Formula: C18H12N6OS Solubility: DMSO (10 mg/ml) DMF (25 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR conforms