Mirin

Overview
Catalog #	bs-82048c-5-mg
Product Name	Mirin
Specifications
Storage Buffer	Tan solid
Storage Condition	-20°C
Target
Product Information	Mirin is an inhibitor of the Mre11-Rad50-Nbs1(MRN) complex (IC50 = 12 µM for inhibition of ATM activity), part of the MRN-ATM(ataxia-telangiectasia mutated) pathway, an essential pathway for sensing and signaling from DNA double-strand breaks. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
Description	CAS Number: 299953-00-7 Chemical Name: 5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one Molecular weight: 220.25 Formula: C10H8N2O2S Solubility: DMSO (30 mg/ml) Physical Properties: Tan solid Purity: 98% by TLC, NMR Conforms