SC-514

Overview
Catalog #	bs-82036c-10-mg
Product Name	SC-514
Specifications
Storage Buffer	yellow solid (MP = 209-211°C)
Storage Condition	RT
Target
Product Information	Reversible, competitive inhibitor of IKK2 (IC50 = 11.2 µM). Has not been demonstrated to inhibit other IKK isoforms, or other kinases. Displays dose-dependent inhibition of the transcription of NK-κB dependent genes in cell culture1.
Description	CAS Number: 354812-17-2 Chemical Name: 5-(Thien-3-yl)-3-aminothiophene-2-carboxamide Molecular weight: 224.3 Formula: C9H8N2OS2 Solubility: DMSO (25 mg/ml) Physical Properties: yellow solid (MP = 209-211°C) Purity: 98% by TLC [5% methanol in methylene chloride; Rf= 0.27] NMR conforms