GW-5074
Overview | |
Catalog # | bs-82018c-5-mg |
Product Name | GW-5074 |
Specifications | |
Storage Buffer | Dark orange solid MP = 267-268°C |
Storage Condition | -20°C |
Target | |
Product Information | Potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable. |
Description | CAS Number: 220904-83-6 Chemical Name: 3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one Molecular weight: 520.95 Formula: C15H8Br2INO2 Solubility: DMSO (50 mg/ml) Physical Properties: Dark orange solid MP = 267-268°C Purity: 98% by TLC NMR conforms |