Pioglitazone HCl

Overview
Catalog #	bs-82002c-10-mg
Product Name	Pioglitazone HCl
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Pioglitazone is a clinically useful antidiabetic drug.1 It is a selective agonist of the human peroxisome proliferator-activated receptor  1(PPAR; EC50 = 490 nM2, 550nM3) with weak agonist activity at PPAR and no activity at PPAR.2 Inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes.4 Suppresses production of inflammatory cytokines and shows antidepressant-like activity in mouse models.5
Description	CAS Number: 112529-15-4 Chemical Name: 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride Molecular weight: 392.090 Formula: C19H20N2O3S ∙ HCl Solubility: DMSO (25 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (conforms)