Jervine

Overview
Catalog #	bs-80500C
Product Name	Jervine
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:425.6 Formula:C27H39NO3 Purity:>98% Solubility:Soluble in DMSO (up to 5 mg/ml), in DMF (up to 6 mg/ml), or in Ethanol (up to 20 mg/ml). Chemical Name:(3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one
Description	Inhibitor of Hedgehog signaling (IC50 = 0.5-0.7 µM). Binds directly to Smoothened (Smo)1. Inhibits the response of target tissues to Sonic hedgehog signaling2. Induces COX-2 overexpression in human erythroleukemia cells3.