DMOG

Overview
Catalog #	bs-80495C
Product Name	DMOG
Specifications
Storage Buffer	powder
Storage Condition	-20°C / protect from light
Target
Product Information	Molecular Weight:175.14 Formula:C6H9NO5 Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Chemical Name:N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Description	Inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1α1,2 and inhibiting JMJD2A (IC50 = 2.5 μM)3. Displays neuroprotective effects. Inhibits neuronal cell death caused by neurotrophin deprivation4. Prevents activation of the ATR/CHK1/p53 pathway and suppresses apoptosis induced by DNA damage5.